Corgi Model for Gene Regulation Released by Nature Communications

Nature Communications has published research on the Corgi model, a context-aware sequence-to-function model for human gene regulation. This model is capable of predicting epigenetic (changes in gene expression without altering DNA sequence) tracks using only RNA-seq data. It also learns cell type-specific trans-regulators (factors that regulate genes from a different location) in a zero-shot manner, meaning it can make predictions for new cell types without prior training on them.